Article

Hydrocephalus caused by <i>Katnip</i> deletion is linked to increased ciliogenesis and reduced proliferation of neuroprogenitor cells

2026-05-05

Abstract excerpt

<h4>Background</h4> KATNIP (Katanin-interacting protein), also known as KIAA0556 , is one of the human genes with pathogenic variants linked to Joubert syndrome, an archetypal neurodevelopmental ciliopathy. KATNIP is a scaffolding protein with a critical role in ciliogenesis. In this study, we characterized the ciliopathy phenotypes due to KATNIP gene deletion. <h4>Results</h4> We produced a Katnip null mous...

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Literature Corpus work: a5356508-fa6e-54b2-b707-9fbd02283c32
DOI: 10.64898/2026.05.01.722314

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