Article

Integrating Genomic Correlation Structure Improves Copy Number Variations Detection

2020-04-09

Abstract excerpt

Copy number variation plays important roles in human complex diseases. The detection of copy number variants (CNVs) is identifying mean shift in genetic intensities to locate chromosomal breakpoints, the step of which is referred to as chromosomal segmentation. Many segmentation algorithms have been developed with a strong assumption of independent observations in the genetic loci, and they assume each locus has a...

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Literature Corpus work: 6c3f7a53-63cf-570f-b90f-f379664ef412
DOI: 10.1101/2020.04.08.032680

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