Article

A peptide-signal amplification strategy for the detection and validation of neoepitope presentation on cancer biopsies

2020-06-12

Abstract excerpt

Targeting the right cancer-specific peptides presented by Human Leukocyte antigen (HLA) class I and II molecules on the tumor cell surface is a crucial step in cancer immunotherapy. Numerous approaches have been proposed to predict the presentation of potential neoepitopes that may be targeted through immune-based therapies. Often founded on patient specific somatic mutations, the routine validation of their actua...

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Literature Corpus work: a4d86497-fc7a-5c52-96e8-84287f92d677
DOI: 10.1101/2020.06.12.145276

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