Article

Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia

2009-03-01

Abstract excerpt

Background: PAX5, a master regulator of B-cell development, was shown to fuse to AUTS2, C20orf112, ELN, ETV6, FOXP1, and ZNF521 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). To determine the overall incidence and the whole spectrum of PAX5 fusion partners in childhood ALL a population-based FISH screening study was performed. Patients: 446 children with de novo ALL registered in the Austrian ALL-BFM-...

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Literature Corpus work: a4c72627-e5ea-5b51-bd1b-fef6f48764c6
DOI: 10.1055/s-0029-1222663

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