Article
DMB labelling for detection and analysis of capsular polysaccharides
2025-01-29
Abstract excerpt
Bacterial capsules are major virulence factors enabling systemic infection by undermining innate and adaptive immunity. Capsular polysaccharides are also the antigen in some of the most successful antibacterial vaccines – including the pneumococcal, neisserial and Hib conjugate vaccines. However, it remains exceptionally challenging to study capsules, primarily due to their high chemical diversity and the limited...
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Identifiers and source
- Literature Corpus work
- a49023e5-0c9a-52db-9047-487fdd94619b
- DOI
- 10.1101/2025.01.29.635457
