Article
In silico typing maps the natural diversity of Escherichia coli transporter-dependent capsules.
Nature microbiology - 1 May 2026
Miravet-Verde Samuel, Cacace Elisabetta, Mores Carine Roese, Rutschmann Christoph, Lin Chia-Wei, Ruscheweyh Hans-Joachim, Cuénod Aline, Barazzone Elisa Cappio, Marrec Enora, Vershynina Kateryna, Schumann Raffael, Bower Dan J, Schubert Mario, Egli Adrian, Fiebig Timm, Slack Emma, Sunagawa Shinichi, Keys Timothy G
Abstract excerpt
Serotyping identifies bacterial variants based on surface antigens, traditionally using antibody-based assays, but has been increasingly replaced by in silico methods that infer serotypes from genomic sequences for faster, scalable and more reproducible analyses. However, traditional Escherichia coli capsule serotyping has largely fallen out of use since the 1990s, leaving gaps in our knowledge of capsule...
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