Article

Natural immunity to pneumococcal Pilus-1 RrgA and RrgB antigens, and its relationship with pneumococcal carriage

2013-01-01

Abstract excerpt

Streptococcus pneumoniae (pneumococcus) is a leading cause of childhood morbidity and mortality around the world. The available polysaccharide-based vaccines are limited by either low efficacy in young children or narrow serotype coverage. Recent research has focused on developing protein vaccines. Pneumococcal pilus-1 proteins play an important role in pneumococcal adherence to host respiratory epithelium and sub...

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Literature Corpus work: a487ff77-79e4-5c04-86b2-9f80ed15cbf9
DOI: 10.17638/00016633

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