Article
Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related.
The Journal of infectious diseases - 15 Mar 2008
Moschioni Monica, Donati Claudio, Muzzi Alessandro, Masignani Vega, Censini Stefano, Hanage William P, Bishop Cynthia J, Reis Joice Neves, Normark Staffan, Henriques-Normark Birgitta, Covacci Antonello, Rappuoli Rino, Barocchi Michèle A
Abstract excerpt
BACKGROUND: Pilus components of Streptococcus pneumoniae encoded by rlrA were recently shown to elicit protection in an animal model of infection. Limited data are available on the prevalence of the rlrA operon in pneumococci; therefore, we investigated its distribution and its antigenic variation among disease-causing strains. METHODS: The prevalence of rlrA and its association with serotype and genotype were...
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