Article

SymPerturb converts symptom-network structure into testable intervention priorities

2026-07-30

Abstract excerpt

Symptom networks encode conditional dependence but do not by themselves identify causal or clinically actionable intervention targets. We introduce SymPerturb, a virtual-perturbation framework that distinguishes four primitive perturbation operators—virtual knockout, virtual knockdown, edge-level communication blocking and node-centred communication blocking—from three analytic procedures—virtual dosage perturbati...

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Literature Corpus work: a43e5293-3f8f-57f5-b621-be30fec2c8b7
DOI: 10.64898/2026.07.27.26359002

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