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Article

Assessing the Role of Model Complexity in Virtual Clinical Trial Outcomes

2025-12-27

Abstract excerpt

Virtual clinical trials (VCTs) hold significant promise for improving the drug development process, yet their predictive reliability depends critically on design decisions that remain poorly understood. This study examines how model complexity influences VCT outcomes, as well as how the choice of prior parameter distributions and virtual patient inclusion criteria affects those outcomes. Using oncolytic virotherap...

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Literature Corpus work
f9ba366d-3f9d-5b10-ab30-9daba0002de7
DOI
10.64898/2025.12.22.25342808
Open publication

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Assessing the Role of Model Complexity in Virtual Clinical Trial OutcomesDOI 10.64898/2025.12.22.25342808
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