Article

Calibrated within-population patient individualisation of antimicrobial exposure: a pre-registered simulation and external-evaluation study

2026-07-13

Abstract excerpt

<title>Abstract</title> <p>Model-informed precision dosing updates a population pharmacokinetic prior with a patient's own measured drug concentrations to individualise the dosing of narrow-therapeutic-index drugs. The approach is established and available in several commercial systems; what must be demonstrated for any particular implementation is that the individual estimates it returns are unbiased, adequately...

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Literature Corpus work: 366bded4-08e9-5e43-b9df-ed889272454f
DOI: 10.21203/rs.3.rs-10299120/v1

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