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Theta, a multidimensional ratio biomarker applied to five amyloid beta peptides for investigations in familial Alzheimer’s disease

2025-08-08

Abstract excerpt

<h4>SUMMARY</h4> Biomarker discovery in complex diseases often requires classifying biological states using multiple, interconnected features, a task where traditional two-feature ratios are limited. We introduce theta, a mathematical model designed to extend the ratio concept for classification across any number of input features. Theta is a multivariate normative statistical model, which quantifies the deviatio...

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Literature Corpus work
a40c154c-5950-5e1b-93b7-aa1973d5f6b6
DOI
10.1101/2025.08.06.25333131
Open publication

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Theta, a multidimensional ratio biomarker applied to five amyloid beta peptides for investigations in familial Alzheimer’s diseaseDOI 10.1101/2025.08.06.25333131
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