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The CentiMarker project: Standardizing quantitative Alzheimer's disease fluid biomarkers for biologic interpretation

1 Apr 2025

Abstract excerpt

INTRODUCTION: Biomarkers play a crucial role in understanding Alzheimer's disease (AD) pathogenesis and treatment effects. However, comparing biomarker measures without standardization and appreciating their magnitude relative to the disease can be challenging. METHODS: To address this issue, we propose the CentiMarker approach, similar to Centiloid, which provides a standardized scale between normal (0) and...

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PMID: 40235082
DOI: 10.1002/alz.14587

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