Article

Beyond P-values: A Multi-Metric Framework for Robust Feature Selection and Predictive Modeling

2025-10-06

Abstract excerpt

High-dimensional biomedical datasets routinely contain sparse signals embedded among vast, correlated features, making variable selection central to building models that generalize. Although significance-based selection is widely used across modalities (e.g., imaging, EHR, multi-omics), statistical significance does not guarantee predictive utility, and vice versa. Yet few methods unify inferential and predictive...

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Literature Corpus work: 36ee2407-fce4-5584-a27e-78f971c952cc
DOI: 10.1101/2025.10.05.680380

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