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Article

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

2 Jul 2016

Abstract excerpt

Biomarkers have become an essential component of Alzheimer disease (AD) research and because of the pervasiveness of AD pathology in the elderly, the same biomarkers are used in cognitive aging research. A number of current issues suggest that an unbiased descriptive classification scheme for these biomarkers would be useful. We propose the "A/T/N" system in which 7 major AD biomarkers are divided into 3 binary...

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PMID: 27371494
DOI: 10.1212/wnl.0000000000002923

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