Article

Case report: A rare BRCA1 de novo variant in a female with breast cancer

2026-01-30

Abstract excerpt

<title>Abstract</title> <p> Background Breast cancer is the most common cancer among women worldwide. While lifestyle factors contribute to rising incidence, 5–14% of cases result from pathogenic variants in core susceptibility genes such as <italic>BRCA1</italic> , which also increases ovarian cancer risk and, in men, prostate cancer risk. <italic>BRCA1</italic> variants are typically autosomal dominant, ma...

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Literature Corpus work: a3e7259b-4d6d-511c-85a8-45a479b6a477
DOI: 10.21203/rs.3.rs-8589545/v1

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