Article

Short T1 Fraction as a Marker of Myelin Content: Evidence from Postmortem MRI and Histology

2026-06-03

Abstract excerpt

<h4>Purpose</h4> To investigate the short-T1 fraction as a potential biomarker of white matter myelin integrity, using myelin histology as ground truth. <h4>Methods</h4> Multi-inversion-time MRI data were acquired from four postmortem brain hemisphere specimens from donors with Alzheimer’s disease on a clinical 3T scanner, and from five dissected tissue blocks containing white matter hyperintensities (WMHs) on a...

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Literature Corpus work: a385a72b-d1ca-5e4c-b64a-71724d789256
DOI: 10.64898/2026.05.31.728778

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