Article

Comprehensive benchmarking of somatic mutation detection by the SMaHT Network

2025-10-10

Abstract excerpt

Somatic mosaicism is increasingly recognized as a fundamental feature of human biology, yet the detection of somatic mutations remains challenging. The SMaHT Network conducted four large-scale benchmarking experiments involving cell-lines and donor tissues, to evaluate sequencing technologies, experimental approaches, and computational methods for detecting different types of somatic mutations, generating communit...

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Literature Corpus work: a3543706-05f8-5895-8fe5-ab97e8276afd
DOI: 10.1101/2025.10.09.678885

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