Article

An unusual and physiologically vital protein with guanylate cyclase and P-type ATPase like domain in a pathogenic protist

2018-11-23

Abstract excerpt

<h4>ABSTRACT</h4> Cyclic GMP is considered as one of the master regulators of diverse functions in eukaryotes; its architecture and functioning in protozoans remain poorly understood however. We characterized an unusual and extra-large guanylate cyclase (477-kDa) containing at least 4 putative P-type ATPase motifs and 21 transmembrane helices in a common parasitic protist, Toxoplasma gondii . This protein, terme...

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Literature Corpus work: a353c80b-6f92-5c57-9a45-4fa55c93692a
DOI: 10.1101/475848

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