Article

Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates

2023-11-08

Abstract excerpt

<h4>Summary</h4> Waning immunity and continued virus evolution have limited the durability of protection from symptomatic infection mediated by intramuscularly (IM)-delivered mRNA vaccines against COVID-19 although protection from severe disease remains high. Mucosal vaccination has been proposed as a strategy to increase protection at the site of SARS-CoV-2 infection by enhancing airway immunity, potentially red...

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Literature Corpus work: a34465e3-db5b-5657-822e-c63d45ffe9b4
DOI: 10.1101/2023.11.06.565765

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