Article

Purine biosynthesis pathways are required for myogenesis in <i>Xenopus laevis</i>

2023-08-18

Abstract excerpt

Purines are required for fundamental biological processes and alterations in their metabolism lead to severe genetic diseases associated with developmental defects whose etiology remains unclear. Here, we studied the developmental requirements for purine metabolism using the amphibian Xenopus laevis as a vertebrate model. We provide the first functional characterization of purine pathway-genes and show that these...

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Literature Corpus work: d8be3739-ce1a-5e05-a4a3-48b1b9ec5f2b
DOI: 10.1101/2023.08.17.553788

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