Article

Nogo-A is critical for pro-inflammatory gene regulation in myocytes and macrophages

2020-10-02

Abstract excerpt

<h4>Background: </h4> Nogo-A (Rtn 4A), a member of the reticulon 4 (Rtn4) protein family, is a neurite outgrowth inhibitor protein that is primarily expressed in the central nervous system (CNS). However, the role of Nogo-A in inflammatory mechanisms remains unclear. Therefore, in this study, we used Nogo-knockout (KO) mice to explore its potential role in the inflammatory process. Here, we investigated whether No...

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Literature Corpus work: a2f7776a-a314-52de-870b-07b47c6f972a
DOI: 10.21203/rs.3.rs-84136/v1

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