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Nogo-A regulates the fate of human dental pulp stem cells towards osteogenic, adipogenic, and neurogenic differentiation

2022-09-01

Abstract excerpt

Human teeth are highly innervated organs that contain a variety of mesenchymal stem cell populations that could be used for cell-based regenerative therapies. Specific molecules are often used in these treatments to favorably modulate stem cells function and fate. Nogo-A, a key regulator of neuronal growth and differentiation, is already used in clinical tissue regeneration trials. While the functions of Nogo-A in...

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Literature Corpus work
cf9e25f2-6aca-5968-afdc-d2ef3e0524e6
DOI
10.1101/2022.09.01.506142
Open publication

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