Article

A most wanted list of conserved protein families with no known domains

2017-10-23

Abstract excerpt

The number and proportion of genes with no known function are growing rapidly. To quantify this phenomenon and provide criteria for prioritizing genes for functional characterization, we developed a bioinformatics pipeline that identifies robustly defined protein families with no annotated domains, ranks these with respect to phylogenetic breadth, and identifies them in metagenomics data. We applied this approach...

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Literature Corpus work: a28f0f88-df84-5eb1-bd17-ac1cbc6332ea
DOI: 10.1101/207985

Open publication

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