Article

Interferon-beta enhances sensitivity to gemcitabine in pancreatic cancer

2020-09-16

Abstract excerpt

<h4>Background: </h4> Adjuvant gemcitabine for pancreatic cancer has limited efficacy in the clinical setting. Impaired drug metabolism is associated with treatment resistance. We aimed to evaluate the chemosensitising effect of interferon-beta (IFN-β) . <h4>Methods: </h4>: BxPC-3, CFPAC-1, and Panc-1 cells were pre-treated with IFN-β followed by gemcitabine monotherapy. The effect on cell growth, colony formation...

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Literature Corpus work: a281e40b-3a2e-5e6b-9430-d5274273fdd6
DOI: 10.21203/rs.3.rs-39801/v3

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