Article

Resolving plasmid-encoded carbapenem resistance dynamics and reservoirs in a hospital setting through nanopore sequencing

2025-08-25

Abstract excerpt

The growing resistance of Enterobacterales to last-resort antibiotics such as carbapenems puts a significant burden on healthcare systems, also due to plasmids driving a rapid spread of carbapenem resistance. We here evaluate the use of long-read nanopore sequencing to investigate carbapenem resistance dynamics and the role of plasmid transfers and environmental reservoirs in the hospital setting. Over 13 months,...

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Identifiers and source

Literature Corpus work: a265db66-ec9d-5624-a3e8-1768e297b507
DOI: 10.1101/2025.08.20.671332

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