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Nanopore metagenomic sequencing links clinically relevant resistance determinants to pathogens

2026-02-18

Abstract excerpt

Culture-independent metagenomics enables the detection of plasmid-encoded antimicrobial resistance (AMR) genes directly from clinical samples; however, the clinical significance of these genes depends on their bacterial host and genomic context, which metagenomics cannot fully infer. Nanopore sequencing technology intrinsically encodes epigenetic modifications such as methylation, which can be leveraged for plasmi...

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Literature Corpus work
e6c47162-e4de-5b95-99eb-e4fa4ce446a5
DOI
10.64898/2026.02.16.706128
Open publication

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Nanopore metagenomic sequencing links clinically relevant resistance determinants to pathogensDOI 10.64898/2026.02.16.706128
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