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Article

Genomically Informed Surveillance for Carbapenem-Resistant Enterobacteriaceae in a Health Care System.

mBio - 28 Jul 2015

Pecora Nicole D, Li Ning, Allard Marc, Li Cong, Albano Esperanza, Delaney Mary, Dubois Andrea, Onderdonk Andrew B, Bry Lynn

Abstract excerpt

UNLABELLED: Carbapenem-resistant Enterobacteriaceae (CRE) are an urgent public health concern. Rapid identification of the resistance genes, their mobilization capacity, and strains carrying them is essential to direct hospital resources to prevent spread and improve patient outcomes. Whole-genome sequencing allows refined tracking of both chromosomal traits and associated mobile genetic elements that harbor...

Topics

Bacterial Proteins
Boston
Carbapenems
DNA, Bacterial
Enterobacter cloacae
Enterobacteriaceae Infections
Epidemiological Monitoring
Genes, Bacterial
Genetic Variation
Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Hospitals

Humans

Klebsiella pneumoniae

Molecular Sequence Data

Plasmids

Polymorphism, Single Nucleotide

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 26220969
DOI: 10.1128/mBio.01030-15
PMCID: PMC4551976

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26220969-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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