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Clinical importance of TYMS and ENOSF1 genetic variants and mRNA expression levels in response to chemotherapy in Iranian gastric cancer patients

2023-05-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Genetic variants are powerful tools for predicting the effectiveness of chemotherapy drugs. Thymidylate synthase (TS) is a crucial enzyme in gastric cancer patients given neoadjuvant chemotherapy based on 5-Fluorouracil (5-FU). The enolase superfamily member 1 (<italic>ENSOF1</italic>) variant affects TS gene (<italic>TYMS</italic>) expression and thus may affect...

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Literature Corpus work
a2523cd1-a88a-5669-bc23-73cb8259ae87
DOI
10.21203/rs.3.rs-2941898/v1
Open publication

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