Article
Clinical significance of UGT1A1 polymorphism and expression of ERCC1, BRCA1, TYMS, RRM1, TUBB3, STMN1 and TOP2A in gastric cancer.
BMC gastroenterology - 5 Jan 2017
Cao Yongkuan, Zhang Guohu, Wang Peihong, Zhou Jun, Gan Wei, Song Yaning, Huang Ling, Zhang Ya, Luo Guode, Gong Jiaqing, Zhang Lin
Abstract excerpt
BACKGROUND: Individualized therapeutic regimen is a recently intensively pursued approach for targeting diseases, in which the search for biomarkers was considered the first and most important. Thus, the goal of this study was to investigate whether the UGT1A1, ERCC1, BRCA1, TYMS, RRM1, TUBB3, STMN1 and TOP2A genes are underlying biomarkers for gastric cancer, which, to our knowledge, has not been performed....
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