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Article

A functional polymorphism in TFF1 promoter is associated with the risk and prognosis of gastric cancer.

International journal of cancer - 1 May 2018

Wang Weizhi, Li Zheng, Wang Jiwei, Du Mulong, Li Bowen, Zhang Lei, Li Qing, Xu Jianghao, Wang Linjun, Li Fengyuan, Zhang Diancai, Xu Hao, Yang Li, Gong Weida, Qiang Fulin, Zhang Zhengdong, Xu Zekuan

Abstract excerpt

Trefoil Factor 1 (TFF1, also named pS2), which serves as the gastrointestinal mucosal protector, is known as gastric-specific tumor suppressor gene. However, the genetic variants of TFF1 are still not well studied. In our study, we aim to explore the effects of tagging single nucleotide polymorphisms (tagSNPs) of TFF1 on risk and prognosis of gastric cancer. Seven tagSNPs of TFF1 gene were first analyzed in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29210057
DOI: 10.1002/ijc.31197

Genes

TFF1
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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