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Exploiting attP landing sites and gypsy retrovirus insulators to identify and study viral suppressors of RNA silencing

2025-02-14

Abstract excerpt

<h4>ABSTRACT</h4> RNA interference (RNAi) pathways are crucial for regulating viral infections in both animals and plants, acting as defense mechanisms that limit pathogen replication. This has led to the evolution of viral suppressors of RNA silencing (VSRs) across various plant and insect viruses, with potential analogs in arthropod-borne human pathogens. However, while functionally similar, VSRs often lack gen...

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Identifiers and source

Literature Corpus work
a247105f-3e86-58cf-9c9c-8f19c2b2d1f5
DOI
10.1101/2025.02.12.637972
Open publication

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