Article

Single-cell characterization of the human C2 dorsal root ganglion recovered from C1-2 arthrodesis surgery: implications for neck pain

2025-03-30

Abstract excerpt

Neurons in the dorsal root ganglion (DRG) receive and transmit sensory information from the tissues they innervate and from the external environment. Upper cervical (C1-C2) DRGs are functionally unique as they receive input from the neck, head, and occipital cranial dura, the latter two of which are also innervated by the trigeminal ganglion (TG). The C2 DRG also plays an important role in neck pain, a common and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a22388e1-8961-54bc-aa4b-f19e624b9ecf
DOI: 10.1101/2025.03.24.645122

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell characterization of the human C2 dorsal root ganglion recovered from C1-2 arthrodesis surgery: implications for neck painDOI 10.1101/2025.03.24.645122Read

<i>IGHG4</i>Expression in C2 Human Dorsal Root Ganglion Potentially Links B Cells to Spreading Chronic Neck PainSemantic proximity Read

A Reference Atlas of the Human Dorsal Root GanglionSemantic proximity Read

RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic painSemantic proximity Read

Spatial transcriptomics reveals unique molecular fingerprints of human nociceptorsSemantic proximity Read

Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptorsSemantic proximity Read

Single nucleus multiomic atlas of human dorsal root ganglia reveals the contribution of non-neuronal cell types to painSemantic proximity Read

Investigation of cellular and molecular changes linked with neuropathic pain in healthy and injured human trigeminal nervesSemantic proximity Read

Single nucleus transcriptomic analysis of human dorsal root ganglion neuronsSemantic proximity Read

Single-nucleus transcriptomic analysis of human dorsal root ganglion neuronsSemantic proximity Read

Transcriptomic analysis of native versus cultured human and mouse dorsal root ganglia focused on pharmacological targetsSemantic proximity Read

Single-cell transcriptomic profiling of dorsal root ganglion: an overviewSemantic proximity Read

Tissue-to-Analysis Framework Enables Multiscale Mapping of the Architectural and Cellular Organization in the Human Dorsal Root GanglionSemantic proximity Read