Article

Interleukin-1 receptor antagonist gene (<i>IL1RN</i>) variants modulate the cytokine release syndrome and mortality of SARS-CoV-2

2023-01-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To explore the regulation of the inflammatory response in acute SARS-CoV-2 infection, we examined effects of single nucleotide variants (SNVs) of IL1RN , the gene encoding the anti-inflammatory IL-1 receptor antagonist (IL-1Ra), on the cytokine release syndrome and mortality. <h4>Methods</h4> We studied 2589 patients hospitalized with SARS-CoV-2 between March 2020 and March 202...

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Literature Corpus work: a200bd23-c0f9-5eca-a604-5c8d55a42879
DOI: 10.1101/2023.01.09.23284348

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