Article

Securinine Inhibits Glioblastoma Growth via the PI3K/AKT/mTOR Signaling Pathway

2026-01-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective</bold> To investigate the mechanism by which securinine inhibits glioblastoma (GBM) growth through the mTOR pathway and its potential application value in promoting GBM apoptosis. <bold/> <bold>Methods</bold> GBM-related target genes and securinine-related target genes were obtained via network pharmacology analysis. In vitro cell experiments (using GBM cell lines...

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Literature Corpus work: a1fc87ea-608e-5881-9cbf-58e7c162d0a1
DOI: 10.21203/rs.3.rs-8631591/v1

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