Article

Persistent Activation of Endothelial Cells is Linked to Thrombosis and Inflammation in Cerebral Cavernous Malformation Disease

2025-07-02

Abstract excerpt

<h4> Abstract </h4> <h4>BACKGROUND</h4> Cerebral cavernous malformations (CCM) are neurovascular lesions that affect both children and adults, and morbidity often results from thrombosis, bleeding, and neurological dysfunction. Studies indicate that inflammation-related activation of endothelial cells contributes significantly to the worsening of CCM disease. This suggests that ongoing vascular inflammation and...

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Literature Corpus work: a1dec0e2-fdec-5ee8-8097-6fb9e9ab24b5
DOI: 10.1101/2025.06.29.662238

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