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Article

Understanding the pathogenesis of brain arteriovenous malformation: genetic variations, epigenetics, signaling pathways, and immune inflammation.

Human genetics - 1 Dec 2023

Wang Shiyi, Deng Xinpeng, Wu Yuefei, Wu Yiwen, Zhou Shengjun, Yang Jianhong, Huang Yi

Abstract excerpt

Brain arteriovenous malformation (BAVM) is a rare but serious cerebrovascular disease whose pathogenesis has not been fully elucidated. Studies have found that epigenetic regulation, genetic variation and their signaling pathways, immune inflammation, may be the cause of BAVM the main reason. This review comprehensively analyzes the key pathways and inflammatory factors related to BAVMs, and explores their...

Topics

Humans
Epigenesis, Genetic
Intracranial Arteriovenous Malformations
Brain
Signal Transduction
Inflammation
Genetic Variation
Activin Receptors, Type II

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37768356
DOI: 10.1007/s00439-023-02605-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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