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Genome-wide identification of pathogenicity factors of the free-living amoeba Naegleria fowleri

19 Jun 2014

Abstract excerpt

BACKGROUND: The free-living amoeba Naegleria fowleri is the causative agent of the rapidly progressing and typically fatal primary amoebic meningoencephalitis (PAM) in humans. Despite the devastating nature of this disease, which results in > 97% mortality, knowledge of the pathogenic mechanisms of the amoeba is incomplete. This work presents a comparative proteomic approach based on an experimental model in...

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PMID: 24950717
DOI: 10.1186/1471-2164-15-496

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