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Health-associated gut bacteriocins target TLR4 to suppress intestinal inflammation

2026-07-23

Abstract excerpt

The human microbiome maintains host immune homeostasis by secreting bioactive metabolites. However, extending beyond well-characterized metabolites, the functions of most microbiome-encoded peptides remain poorly defined. In this study, we developed a multi-cohort metagenomic framework to profile protective class II bacteriocins—unmodified, ribosomally synthesized peptides—that are enriched in healthy individuals...

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Literature Corpus work
998939ae-a931-5d5a-9b5a-2329e2ec4cf9
DOI
10.64898/2026.07.22.739491
Open publication

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Health-associated gut bacteriocins target TLR4 to suppress intestinal inflammationDOI 10.64898/2026.07.22.739491
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