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Impaired Immunosuppressive Effect of Bone Marrow Mesenchymal Stem Cell-derived Exosomes on T cells in Aplastic Anemia

2023-04-26

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Previous studies haveverified the dysfunction of mesenchymal stem cells (MSCs) for immunoregulation in acquired aplastic anemia (AA) patients. Exosomes derived from MSCs can partially substitute MSCs acting as immune regulator. Dysfunction of exosomes (Exos)derived from AA-MSC (AA-Exos) may play a key role in immunologic dissonance. <bold>Method:</bold> In this...

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Literature Corpus work
a19b5192-a7d8-50e9-92a7-7faf0f5dad55
DOI
10.21203/rs.3.rs-2596020/v1
Open publication

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Impaired Immunosuppressive Effect of Bone Marrow Mesenchymal Stem Cell-derived Exosomes on T cells in Aplastic AnemiaDOI 10.21203/rs.3.rs-2596020/v1
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