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MiR-223 Derived from Mesenchymal Stem Cell Exosomes Alleviates Acute Graft-Versus-Host Disease

2020-05-19

Abstract excerpt

<h4>Background: </h4> Mesenchymal stem cells (MSCs) have been utilized in treating acute graft-versus-host disease (aGvHD) as they show strong immunosuppressive capacity, but the mechanisms are not well defined. <h4>Methods: </h4> In this study, we demonstrated that microRNA-223 (miR-223) derived from exosomes secreted by human umbilical cord mesenchymal stem cells (huc-MSCs) and murine compact bone mesenchymal st...

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Literature Corpus work
c47eea73-54b6-51ce-9e1f-1f24c5140423
DOI
10.21203/rs.3.rs-28347/v1
Open publication

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