Article
Praziquantel inhibits <i>Caenorhabditis elegans</i> development and species-wide differences might be cct-8-dependent
2023-05-19
Abstract excerpt
<h4>ABSTRACT</h4> Anthelmintic drugs are used to treat parasitic roundworm and flatworm infections in humans and other animals. Caenorhabditis elegans is an established model to investigate anthelmintics used to treat roundworms. In this study, we use C. elegans to examine the mode of action and the mechanisms of resistance against the flatworm anthelmintic drug praziquantel (PZQ), used to treat trematode and c...
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Identifiers and source
- Literature Corpus work
- f3fc1458-d3ba-541b-839a-4e2edefa753b
- DOI
- 10.1101/2023.05.17.541211
