Article

Dysregulated Expression of Circadian Genes in Lymphoblastoid Cells of Patients with ASD

2022-10-07

Abstract excerpt

Patients with Autism Spectrum Disorder (ASD) often exhibit disturbances in sleep, metabolism, and immune system. The molecular mechanisms for these clinical features in ASD are currently unknown. We demonstrated that circadian genes in the cells of patients with ASD often are dysregulated compared to controls. The dysregulation of circadian genes was reflected in two different ways: (1) abnormal levels of expressi...

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Literature Corpus work: a15f5b13-77d5-5fe0-80e4-f5a528e33b3c
DOI: 10.1101/2022.10.03.510736

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