Article

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancer

2023-03-24

Abstract excerpt

<h4>ABSTRACT</h4> Head and neck cancers are a complex malignancy comprising multiple anatomical sites, with cancer of the oral cavity ranking among the deadliest and most disfiguring cancers globally. Oral cancer (OC) constitutes a subset of head and neck cancer cases, presenting primarily as tobacco-and alcohol-associated oral squamous cell carcinoma (OSCC), with a 5-year survival rate of ∼65%, partly due to the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9c16c6c3-8472-5019-b7cc-197f8d1db5e1
DOI: 10.1101/2023.03.24.534064

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancerDOI 10.1101/2023.03.24.534064Read

Total RNA sequencing reveals gene expression and microbial alterations shared by oral pre-malignant lesions and cancerSemantic proximity Read

Oral microbiome profiles in oral potentially malignant disorders and oral cancer – A diagnostic perspectiveSemantic proximity Read

Molecular landscapes of oral cancers of unknown etiologySemantic proximity Read

Oral Squamous Cell Carcinoma: A Comprehensive Review of Risk Factors, Molecular Pathogenesis, and Prevention StrategiesSemantic proximity Read

Mutational signature-based classification uncovers emerging oral cancer subtypes with distinct molecular patterns.Semantic proximity Read

Oral Potentially Malignant Disorders: Etiology, Pathogenesis, and Transformation Into Oral CancerSemantic proximity Read

Oral Microbiome: A New Biomarker Reservoir for Oral and Oropharyngeal CancersSemantic proximity Read

Integrative analysis of spatiotemporal transcriptomics delineates dynamic cell states in squamous tumorigenesisSemantic proximity Read

Integrative metatranscriptomic analysis reveals disease-specific microbiome-host interactions in oral squamous cell carcinomaSemantic proximity Read

Transcriptional reprogramming in oral squamous carcinomaSemantic proximity Read

Single-cell and spatial dissection of precancerous lesions underlying the initiation process of oral squamous cell carcinomaSemantic proximity Read

Role of Oral Microbiome Signatures in Diagnosis and Prognosis of Oral CancerSemantic proximity Read