Article

Adipose-tissue derived signals control bone remodelling

2020-03-03

Abstract excerpt

<h4>Summary</h4> Long bones from mammals host blood cell formation and contain multiple cell types, including adipocytes. Physiological functions of bone marrow adipocytes are poorly documented. Herein, we used adipocyte-deficient PPARγ-whole body null mice to investigate the consequence of total adipocyte deficiency on bone homeostasis in mice. We first highlight the dual bone phenotype of PPARγ null mice: on th...

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Literature Corpus work: 1d293874-dead-5046-a607-fcb4cd200c37
DOI: 10.1101/2020.03.02.972711

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