Article

The conserved two-component systems CutRS and CssRS control the protein secretion stress response in Streptomyces species

2025-03-20

Abstract excerpt

<h4>ABSTRACT</h4> Streptomyces secondary metabolites account for over half of all clinically used antibiotics, as well as numerous antifungal agents, anticancer compounds, and immunosuppressants. Two-component systems, which are widespread in bacteria, are key regulators of antibiotic production in Streptomyces species, yet their activating signals remain poorly understood. CutRS was the first two-component syst...

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Literature Corpus work: a0473bee-4c31-50ce-a244-76341c1f9514
DOI: 10.1101/2025.03.20.644377

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