Article
A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis.
Journal of bacteriology - 1 Oct 2002
Darmon Elise, Noone David, Masson Anne, Bron Sierd, Kuipers Oscar P, Devine Kevin M, van Dijl Jan Maarten
Abstract excerpt
Bacteria need dedicated systems that allow appropriate adaptation to the perpetual changes in their environments. In Bacillus subtilis, two HtrA-like proteases, HtrA and HtrB, play critical roles in the cellular response to secretion and heat stresses. Transcription of these genes is induced by the high-level production of a secreted protein or by a temperature upshift. The CssR-CssS two-component regulatory...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Base Sequence
- Gene Expression Regulation, Bacterial
- Heat-Shock Proteins
- Hot Temperature
- Molecular Sequence Data
- Mutation
- Operon
- Periplasmic Proteins
- Promoter Regions, Genetic
- Serine Endopeptidases