Article
The cutRS signal transduction system of Streptomyces lividans represses the biosynthesis of the polyketide antibiotic actinorhodin.
Molecular microbiology - 1 Sept 1996
Chang H M, Chen M Y, Shieh Y T, Bibb M J, Chen C W
Abstract excerpt
The nucleotide sequence of a two-component signal transduction operon (cutRS) of Streptomyces lividans TK64 was elucidated. Transcription of the operon was detected during the transition and stationary phases of growth, initiating at a single site upstream of cutR. This promoter region also posse...
Topics
- Amino Acid Sequence
- Anthraquinones
- Anti-Bacterial Agents
- Bacterial Proteins
- Base Sequence
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Operon
- Phenotype
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Signal Transduction
- Streptomyces
- Time Factors
- Transcription Factors
- Transcription, Genetic