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Article

Role of detrusor PDGFRα+ cells in Cyclophosphamide-induced Detrusor Overactivity

2022-02-21

Abstract excerpt

Cyclophosphamide (CYP)-induced cystitis is a rodent model that shares many features common to the cystitis occurring in patients, including detrusor overactivity (DO). Platelet-derived growth factor receptor alpha positive (PDGFRα+) cells regulate muscle excitability in murine bladders during filling. PDGFRα+ cells express small conductance Ca2+-activated K+ channels (predominantly SK3) that provide stabilization...

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Literature Corpus work
a0301317-bbaf-55b6-80db-30f7acd26196
DOI
10.21203/rs.3.rs-653727/v2
Open publication

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Role of detrusor PDGFRα+ cells in Cyclophosphamide-induced Detrusor OveractivityDOI 10.21203/rs.3.rs-653727/v2
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