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Article

Function and expression pattern of TRPM8 in bladder afferent neurons associated with bladder outlet obstruction in rats.

Autonomic neuroscience : basic & clinical - 28 Oct 2011

Hayashi Tokumasa, Kondo Teruyoshi, Ishimatsu Masaru, Takeya Mitsue, Igata Sachiyo, Nakamura Kei-ichiro, Matsuoka Kei

Abstract excerpt

We investigated the function and expression pattern of the transient receptor potential melastatin-8 (TRPM8) in urinary bladder afferent neurons from control and bladder outlet obstruction (BOO) rats. BOO was produced and, after six weeks, the effects of intravesical infusion of menthol, the agonist of TRPM8, were investigated using unanesthetized cystometry. The intravesical infusion of menthol produced an...

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Source

Identifiers

PMID: 21684817
DOI: 10.1016/j.autneu.2011.05.006

Genes

TRPM8
TRPV1

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